Scientists at the Universities of Liverpool and Glasgow have uncovered a possible new method of enhancing nerve repair in the treatment of spinal cord injuries.
It is known that scar tissue, which forms following spinal cord injury, creates an impenetrable barrier to nerve regeneration, leading to the irreversible paralysis associated with spinal injuries. Scientists at Liverpool and Glasgow have discovered that long-chain sugars, called heparan sulfates, play a significant role in the process of scar formation in cell models in the laboratory. Research findings have the potential to contribute to new strategies for manipulating the scarring process induced in spinal cord injury and improving the effectiveness of cell transplantation therapies in patients with this type of injury.
Research published online Monday in the Journal of the American Medical Association finds that taking a daily multivitamin offers no more protection against heart attack, stroke or death from cardiovascular disease than taking a daily placebo pill. The study was based on the Physicians’ Health Study II (PHS II), a randomized, double-blind, placebo-controlled trial that began in 1997 and ran through June 1, 2011. It included 14,641 male physicians (754 with a history of cardiovascular disease) who were 50 years or older at the start of the study. About half (7,317) of the men were randomly assigned to take a daily Centrum multivitamin; the other half (7,324) were assigned to take placebo pills.
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